At the University of Maryland, researchers have found a new way to treat bites from venomous snakes: using protective proteins from their blood. They turned out to be about 10 times more effective than standard antivenom. In experiments, protein combinations completely neutralized the deadly venom of the western diamondback rattlesnake and protected against the venoms of other vipers.
The logic seems simple: if snakes do not die from their own venom, the natural protection in their blood can be used to treat bites. But first, the team had to determine which proteins were responsible. They identified FETUA-3, which blocks the action of toxins, and then found that combinations were especially effective. Some proteins suppress venom enzymes, while others prevent bleeding.
The development is especially important for poorer regions: snakebites kill 80,000 to 140,000 people each year. The next step is to create recombinant antivenoms that can be produced using biotechnology without animals.
